At a high level, there is not much of a difference between most distributions. They’re all shipping the same software more or less. Zoomed in, there are some differences which may be of interest to you. Things like project governance, frequency of releases (or potentially, a “rolling release”), distribution architecture (how the package manager and package repositories are set up), whether the distribution does custom branding and spit-shine or they distribute software exactly as published by the upstream developers.

Gaming is one of the most common use-cases. You won’t have a hard time installing the Nvidia driver or Steam on any distribution for instance, unless it is a distribution designed exclusively to distribute free software.

but also those who do modern gaming on Linux.

I play just about anything on Gentoo. Native Linux titles, Windows titles through Wine/Proton. Multiple classic systems through emulators ranging from NES to PS3. The main potential sore spot is multiplayer games which require intrusive anti-cheat systems. These typically don’t work, but with increasing motivation for publishers to make their games work on Steam Deck, some systems like Easy AntiCheat can work if the publisher chooses (Elden Ring is one example).