As your stomach fills and stretches it sends a chemical “I’m full” message (GLP1) to the brain. When this signal is low you are hungary, medium you are full, and high you get nauseous.

Ozempic causes that message to be produced at low constant levels in addition to what is produced by the stomach.

So you don’t feel as hungry, you hit satiety faster, and if you continue to eat you get nauseous. This results in behaviors that reduce calorie consumption.

It also delays gastric emptying which also keeps you feeling full longer.